What indicates an "altered oxygenation" status in a neonate that requires immediate intervention?

An altered oxygenation status in a neonate is characterized by low oxygen saturation levels (SpO2) that persist even when there is a high fraction of inspired oxygen (FiO2). This condition suggests that the neonate is unable to effectively oxygenate their blood, which may be due to underlying respiratory or cardiac issues. When a neonate exhibits low SpO2 values despite being provided with a high level of oxygen, it indicates that standard interventions may not be sufficient and that immediate assessment and intervention are crucial to prevent further complications or deterioration.

In contrast, stable blood gas values, a normal respiratory rate, and a stable heart rate do not necessarily indicate problems with oxygenation. These parameters may reflect a stable clinical state where the neonate is adequately oxygenated and does not require urgent intervention. Therefore, the presence of low SpO2 in the context of high FiO2 is a critical finding that necessitates prompt attention.